To effectively solve the problem of uncertain response of source and load in active distribution network(ADN)
the source-side and load-side interacting probabilistic load flow model is set up based on the traditional probabilistic load flow model. The power exchange volatility between the virtual microgrid and distribution network and the uncertainty of demand response are regarded as random variables injection. Accordingly
the optimal operation strategy by coordinating the source and load is generated with the optimization objective of minimizing the ADN operation cost and determining the source-side and load-side responses. This model can not only avoid the situation of the superior main network bearing the unbalanced power
but also boost the security and economy of the system. The validity and practicability of the optimal operation strategy are verified by the results of simulation.