A novel series hybrid active power filter（SHAPF）based on fundamental magnetic flux compensation（FMFC）is proposed to used in the high voltage level electric power system.The working principle of the SHAPF，the engineering design of series transformer and the inverter are introduced.Experimental results of engineering application prove that this SHAPF based on FMFC is good in the harmonic mitigation and reliability.The harmonic voltage on the series transformer has little influence to load voltage waveform.In addition，experimental results also prove that the harmonic mitigation effect is good when there is no passive power filter working.This SHAPF based on FMFC can be used in high voltage and large capacity electric power system.