After large-scale blackout, it is of great significance for effective network reconfiguration to formulate a rational restoration sequence under the constraint of ensuring system operation security to restore the output of units as quickly as possible. A method for network reconfiguration and sequence optimization based on goal programming is proposed with the duration of reconfiguration and the restoration of units output as the main items for evaluation of the effects of reconfiguration. Furthermore, a model of goal programming is developed that takes into account different weights of sub-goals and the sum of total differences in target values. The application to an IEEE 30 power system shows that the method can make full use of the incompatibility of different objectives to most emphatically bring out the decision preference regarding target values.