In typical six-phase transmission system， half positive sequence， half zero sequence and half negative sequence fault components are independent of the variance of system impedance. A new comprehensive scheme， i.e. directional comparison pilot protection for six-phase transmission lines is presented based on the above mentioned three fault sequence components. It can automatically select the proper criterion according to the characteristics of faults， and reflect all faults except 6-phase fault on a transmission line. By adding positive sequence fault components of voltage and current， it can identify the direction of 6-phase fault. The results of EMTDC simulation confirm that the proposed scheme is unaffected by system impedance and transition resistance. Hence it is simple， reliable and rapid.