As wind farm has been and will be massively integrated into power backbone grid, power system dispatch and control is confronted with new challenges. The active power dispatch mode for interconnected power grids with large-scale wind power integration is analyzed, and it is concluded that the conventional local balance mode in a provincial grids can no longer resist large-scale wind power fluctuations. Then a centralized control mode of reallocating all generation resources of whole interconnected power grids is presented. And the characteristics of the proposed mode are analyzed, including active power balance method, active power control mainstay, resources allocation, interchange power, security constraint and data communication. Furthermore, to adapt to the current availability of dispatch system and technology foundation in China, a new solution is presented, which takes centralized control mode as goal and hierarchical coordinative control mode as transition.The work is supported by National Mega-project of Science Research for the 11th Five-year Plan(No. 2008BAA13B06).