To solve the problem of lacking of integrated protection model in power system simulation, the virtual protection modeling and simulation system(VPMS) based on flexible simulation technology and hybrid Petri net is introduced. According to the characteristics of relay protection and requirements of protection modeling, the hybrid time Petri net(HTPN) model is proposed to be the foundation of VPMS. Many sorts of protection components and algorithm modules are programmed and can be considered to produce the protection model. Using modeling method of multi-way and multi-layer, the protection model becomes hybrid and of multi-resolution, which meets the requirements of various simulation situations. Using flexible simulation theory, program modules with special functions are developed and can be easily combined into templates for various applications. Under uniform management and control of a simulation engine, the protection model is imported to power system transient, middle and long term dynamic simulation with VPMS, which has important practical value for the study of power grid cascading fault analysis, protection testing, new principle development, protection settings and so on.