This paper studies the application of virtual instrument technology on power quality calibration device. Its function principle, hardware configuration and design idea of the test software developed by LabVIEW program are introduced in details. The device is composed of arbitrary wave generator, power amplifier, data acquisition system, control computer and LabVIEW software platform. The output-calibrated signal is generated by the software platform and monitored by the data acquisition system. The device can be used to calibrate and verify the power quality analyzers. In fact, the metrological device based on virtual instrument technology has many characteristics, such as user-friendly interface, advanced automation, convenient operation, high reliability and high accuracy.