Different types of preventive control with consideration of the same power system are taken through the same dispatching schedule in control center， so they must be coordinated. The concept， mathematic model and solution for coordinated preventive control（CPC） with consideration of comprehensive security are discussed. First， the model of comprehensive security constrained optimal power flow（GSC-OPF） is constructed. This model can be applied in two situations， i.e. preventive control of current operation point and improving the TTC. The comprehensive security constraint is decomposed into three sub constraints: operation feasible constraint， dynamic security constraint and static voltage stability constraint. Then the successive linear programming（SLP） based on the sensitivity matrixes is developed to solve this model. At last， the CPC strategy is testified correct and efficient through digital tests on a New England 10-generator 39-bus system.